Description

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(TFMPP) 3-Trifluoromethylphenylpiperazine is a recreational drug of the piperazine chemical class. Usually in combination with benzylpiperazine and other analogues, it is sold as an alternative to the illicit drug MDMA

-Trifluoromethylphenylpiperazine (TFMPP) is a recreational drug of the piperazine chemical class. Usually in combination with its analogue benzylpiperazine (BZP), it is sold as an alternative to the illicit drug MDMA (“Ecstasy”) under the name “Legal X”.TFMPP is rarely used by itself. In fact, TFMPP reduces locomotor activity and produces aversive effects in animals rather than self-administration, which may explain the decision of the DEA not to permanently make TFMPP a controlled substance

UPAC name: 1-[3-(trifluoromethyl)phenyl]piperazine
Other name: Trifluoromethylphenylpiperazine
CAS number: 15532-75-9
Formula: C11H13F3N2
Purity: 99,8% min

Appearance: white powder

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The dosage commonly used when combined with BZP for “ecstasy-like effects” is between 30 and 100 mg, while higher doses of TFMPP alone cause mildly hallucinogenic effects at around 100–250 mg; however, higher doses can cause a range of side effects including migraine headaches, muscle aches, nausea and vomiting, as well as a come-down syndrome characterized by insomnia, loss of appetite, and headache

The drug can also cause the body to tremble for a long period of time.

The technical stuff you should know

TFMPP has affinity for the 5-HT1A (Ki = 288 nM), 5-HT1B (Ki = 132 nM), 5-HT1D (Ki = 282 nM), 5-HT2A (Ki = 269 nM), and 5-HT2C (Ki = 62 nM)receptors, and functions as a full agonist at all sites except the 5-HT2A receptor, where it acts as a weak partial agonist or antagonist.[4] Unlike the related piperazine compound meta-chlorophenylpiperazine (mCPP), TFMPP has insignificant affinity for the 5-HT3 receptor (IC50 = 2,373 nM).TFMPP

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